As shown in issue11400, the pool can be refresh at any time since rev 32cd371b3e9c and so code using pool instance can also in many cases:

• The pool instance has no more objects, this can be solved by storing the _pool on the instance
• The pool singleton for a database can be stopped (not initialized) at any time. I see at least two possible solutions:
  • Keep the previous pool instance and use it as fallback if the current one is not initialized
  • Raise a specific exception so the dispatcher, cron or worker can retry it with a initialized pool.